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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PEX1
All Species:
24.85
Human Site:
S1209
Identified Species:
34.17
UniProt:
O43933
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43933
NP_000457.1
1283
142867
S1209
I
I
K
G
R
Y
R
S
Q
S
G
E
D
E
S
Chimpanzee
Pan troglodytes
XP_519198
1283
142803
S1209
I
I
K
G
R
Y
R
S
Q
S
G
E
D
E
S
Rhesus Macaque
Macaca mulatta
XP_001101055
1278
142022
S1204
I
I
K
G
R
Y
Q
S
Q
S
G
E
D
E
S
Dog
Lupus familis
XP_532459
1267
140567
S1193
V
I
K
G
R
Y
Q
S
Q
S
G
E
E
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5BL07
1284
141409
S1210
I
I
K
G
R
Y
R
S
Q
S
G
E
D
E
S
Rat
Rattus norvegicus
P46462
806
89330
R733
D
P
V
P
E
I
R
R
D
H
F
E
E
A
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520628
1178
126535
S1103
A
I
K
D
S
Y
R
S
P
S
R
D
E
E
P
Chicken
Gallus gallus
XP_418655
1290
143066
S1217
A
L
K
A
N
Y
R
S
K
N
G
E
D
S
T
Frog
Xenopus laevis
P23787
805
89193
R732
D
D
P
V
P
E
I
R
R
D
H
F
E
E
A
Zebra Danio
Brachydanio rerio
Q7ZU99
806
89405
K733
D
P
V
P
E
I
R
K
D
H
F
E
E
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KN62
801
88841
E728
D
E
D
D
P
V
P
E
I
T
S
A
H
F
E
Honey Bee
Apis mellifera
XP_397107
1069
120490
E996
E
G
Y
F
G
M
N
E
T
A
W
M
V
V
C
Nematode Worm
Caenorhab. elegans
P54812
810
89622
V737
E
D
E
L
A
D
P
V
P
E
I
T
R
A
H
Sea Urchin
Strong. purpuratus
XP_797089
1508
166130
G1434
N
Y
T
R
K
M
A
G
E
S
V
G
G
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCN8
815
90322
S742
K
A
G
H
F
E
E
S
M
K
Y
A
R
R
S
Baker's Yeast
Sacchar. cerevisiae
P24004
1043
117258
V970
K
T
L
L
Q
Q
D
V
V
H
E
T
K
T
S
Red Bread Mold
Neurospora crassa
Q7SGP2
1381
148356
K1298
M
F
E
G
A
K
D
K
D
K
K
K
E
G
A
Conservation
Percent
Protein Identity:
100
99.6
92.8
86.4
N.A.
82
23.3
N.A.
52.4
62.4
22.9
22.8
N.A.
23.6
27.6
22.1
35.2
Protein Similarity:
100
100
94.9
92
N.A.
89.5
39.2
N.A.
66
77.6
38.6
39
N.A.
37.6
46.7
38.4
53.2
P-Site Identity:
100
100
93.3
73.3
N.A.
100
13.3
N.A.
46.6
46.6
6.6
13.3
N.A.
0
0
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
60
73.3
26.6
20
N.A.
6.6
6.6
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
25.7
21.4
Protein Similarity:
N.A.
N.A.
N.A.
38.5
45.2
40.9
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
6
0
6
12
0
6
0
0
6
0
12
0
18
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
6
% C
% Asp:
24
12
6
12
0
6
12
0
18
6
0
6
30
6
0
% D
% Glu:
12
6
12
0
12
12
6
12
6
6
6
48
36
36
6
% E
% Phe:
0
6
0
6
6
0
0
0
0
0
12
6
0
6
0
% F
% Gly:
0
6
6
36
6
0
0
6
0
0
36
6
6
6
0
% G
% His:
0
0
0
6
0
0
0
0
0
18
6
0
6
0
6
% H
% Ile:
24
36
0
0
0
12
6
0
6
0
6
0
0
0
0
% I
% Lys:
12
0
42
0
6
6
0
12
6
12
6
6
6
0
0
% K
% Leu:
0
6
6
12
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
6
0
0
0
0
12
0
0
6
0
0
6
0
0
12
% M
% Asn:
6
0
0
0
6
0
6
0
0
6
0
0
0
0
0
% N
% Pro:
0
12
6
12
12
0
12
0
12
0
0
0
0
6
6
% P
% Gln:
0
0
0
0
6
6
12
0
30
0
0
0
0
0
0
% Q
% Arg:
0
0
0
6
30
0
42
12
6
0
6
0
12
6
0
% R
% Ser:
0
0
0
0
6
0
0
48
0
42
6
0
0
6
42
% S
% Thr:
0
6
6
0
0
0
0
0
6
6
0
12
0
6
12
% T
% Val:
6
0
12
6
0
6
0
12
6
0
6
0
6
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% W
% Tyr:
0
6
6
0
0
42
0
0
0
0
6
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _